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Analysis

One model writes personality questions, another picks compounds for living skin

GPT-4 generated personality questionnaires and predicted response patterns. Outer Biosciences uses a model to choose which cosmetic compound to test on skin tissue kept alive for up to a month.

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A pipette applies an amber droplet to living skin tissue in a transparent perfusion chamber, surrounded by a microscope and unlabelled laboratory vessels.

GPT-4 generated personality questionnaires from two texts

Researchers at the Hebrew University of Jerusalem gave GPT-4 two different source texts: DSM-5 and an astrology textbook. The model generated personality questionnaires from them. About 600 participants completed the resulting questions alongside the Big Five personality inventory. The DSM-5-based questionnaires showed high internal consistency within personality clusters; the questionnaire derived from the astrology text did not. The comparison showed that the model did not produce the same measurement quality from the two source texts when turning their structures into questions.[1]

The model predicted response patterns before the survey

The study by Rotem Monsa, Aviv Zohar and Shahar Arzy was published in iScience. Before giving the questions to participants, the researchers asked the model to anticipate population-level response distributions and correlations among questions. The report says the model predicted those patterns accurately. The experiment tested how much of a measurement instrument's structure a language model could reproduce. The result does not provide evidence that the model understands the people who answered the questions.[1]

Outer Biosciences uses a model to choose chemicals for living skin

Outer Biosciences keeps human skin tissue alive outside the body for up to a month, compared with an industry norm of a few days. The company uses a model to select untested chemicals expected to affect a particular skin function. Results from the living tissue return to the model, and a new candidate enters the loop about every 6 weeks. The company has six active leads with several dozen further hits behind them. It targets cosmetic ingredients rather than drugs. Outer has raised about 23 million dollars and employs 19 people.[2]

References

  1. News sourceThe Jerusalem PostA model wrote the personality test, then predicted how people would answer it↩1↩2
  2. News sourceTechCrunchOuter Biosciences keeps skin alive for a month, and a model picks what to test on it↩