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A DNA network gives a restless fluid a shared rhythm

Long DNA chains brought coordinated motion to a laboratory fluid stirred by molecular motors. As the flow stretched and tangled the chains, their growing network linked distant regions and supported oscillations across millimetres. The peer-reviewed experiment offers a physical explanation for collective motion in a deliberately simplified material, with chain length and motor activity helping determine its behaviour.

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A glass flow channel filled with transparent liquid and its illumination equipment inside a freestanding enclosure in a soft-matter physics laboratory.

Distant regions began moving together

A fluid assembled from biological components developed a rhythm across millimetres when long DNA chains formed an internal network. The peer-reviewed Nature Physics experiment used DNA as a flexible material in a laboratory mixture. Protein filaments called microtubules supplied tracks for kinesin, an energy-consuming molecular motor. As those motors drove motion, the DNA carried mechanical stresses between regions that previously moved without a common rhythm.[1]

The network changed before becoming a sheet

The researchers followed fluorescently labelled components and tracer particles to examine how motion spread. Mixtures lacking DNA retained disordered flows. With long chains, the network progressively reorganized and the flow repeatedly reversed across larger regions. The DNA later contracted towards a thinner sheet, but the oscillations had already started. That sequence supported a mechanical connection through a three-dimensional network rather than requiring a fully flattened structure first.[1]

Chain length and motor activity shaped the rhythm

Shorter DNA chains left the material disordered or showed vortices that faded. Persistent oscillations emerged with longer chains. A theoretical model related the transition to the interaction of motor forces with a network that stores and releases stress. Changing channel width and motor activity also changed the oscillation period. The authors proposed this feedback as a design principle for self-organizing soft materials; the result concerns their simplified experimental composite.[1]

References

  1. News sourceNature PhysicsA DNA network turns disordered flow into coordinated millimetre-scale oscillations↩1↩2↩3